Efficacy of low-level laser therapy enhances the rate of canine retraction by increasing β glucoronidase and pentraxin – 3 in gingival crevicular fluid: A clinical study

---

Original Article

Author Details : Unnati Dinesh Parekh*, Shraddha Shetti, Jiwanasha Manish Agrawal, Manish Agrawal, Sangamesh Fulari, Someshwar Golgire

Volume : 8, Issue : 3, Year : 2024

Article Page : 307-313

https://doi.org/10.18231/j.jco.2024.046

Suggest article by email

---

Abstract

Aim: The aim of the study was to evaluate the efficacy of low-level laser therapy in enhancing the rate of orthodontic tooth movement using β glucoronidase and pentraxin-3 (TNF) biomarkers in gingival crevicular fluid.
Materials and Methods: A split-mouth design was used in 16 subjects (8 experimental and 8 controlled) aged 14 to 25 years, who’s maxillary first premolars were extracted. A gallium-aluminium-arsenide semiconductor diode laser (wavelength, 810 nm; energy density, 10 J/cm2; power output, 100 mW) delivered low-level laser therapy to the experimental canine undergoing distalization at 10 points. The control canine was distalized without low-level laser therapy. The experimental and control canines were distalized using a force of 150 g provided by nickel-titanium closed coil springs. Gingival crevicular fluid was collected at 5 time points from the control and experimental sides, and the levels of β glucoronidase and pentraxin-3 were analysed by enzyme-linked immuno-sorbent assay (ELISA). The rate of canine retraction was calculated by using ortho analyser software.
Results: Increased levels of β glucoronidase and pentraxin-3 were observed in the experimental canines compared with the control canines (P <0> Conclusion: Low level laser therapy in adjunct with continuous and light forces leads to increase in β glucoronidase and pentraxin-3 leading to accelerated orthodontic tooth movement.
Clinical Significance: Low-level laser therapy fastens the rate of canine retraction thus accelerating the orthodontic tooth movement. The levels of β glucoronidase and Pentraxin 5 are increased significantly after laser irradiation which aids in accelerating orthodontic tooth movement.

Keywords: Accelerated orthodontics, Gingival crevicular fluid, Low level laser therapy, Rate of retraction

How to cite : Parekh U D, Shetti S, Agrawal J M, Agrawal M, Fulari S, Golgire S, Efficacy of low-level laser therapy enhances the rate of canine retraction by increasing β glucoronidase and pentraxin – 3 in gingival crevicular fluid: A clinical study. J Contemp Orthod 2024;8(3):307-313

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International, which allows others to remix, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.