Effect of fluoride releasing materials on white spot lesions during orthodontic treatment assessed using QLF device – An in-vivo study

• Author Details:   
• Dinesh Maddhesia
• Mridul Khanduri
• Ajay Gupta
• Taruna Puri
• Varun Kashyap
• Anita Bishnoi ^*

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Introduction and objectives: One of the pitfalls of orthodontic therapy is the appearance of white spot lesions (WSL’s) around brackets within 4 weeks of bracket placement while, regular caries formation usually takes 6 months. Hence, the present study was designed to assess the effect of different fluoride-releasing materials on white spot lesions using Quantitative light-induced florescence (QLF) device.

Materials and Methods: 120 patients who were eligible for this in vivo study were categorized into four groups (30 patients per group) depending on the use of different fluoride remineralizing agents as Group A: Control Baseline Group, Group B: Sodium fluoride 0.2% (Dr Reddy’s Senquel AD mouthwash), Group C: Sodium monoflurophosphate 0.7% (Dr Reddy’s Senquel F toothpaste) and Group D: Sodium fluoride 5% GC MI Varnish TM (Casein phospho peptide amorphous calcium phosphate). WSLs were evaluated at T0, T1 (1 week), T2 (2 week) and T3 (4 weeks) time intervals. MANOVA and Post hoc tests were used for the analysis of data.

Result All material showed significant results in all time intervals compared with group A, when compared within the fluoride-releasing groups, fluoride varnish was found to be more effective and superior in its ability to remineralize white spot lesions at T1 to T2 time intervals.

Conclusion All the materials in the present study helped in the prevention of WSLs depending upon patients’ compliance. Order of prevention of WSLs was fluoride varnish ≥ fluoride toothpaste > mouthwash. Clinical significance Fluoride releasing materials such as fluoride varnish and toothpaste have similar remineralizing effect on WSLs till 2 weeks and fluoride varnish effect deteriorated after 3 weeks. Hence, repeated applications for maximum benefit are recommended