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- DOI doi: 10.18231/j.jco.8168.1758887466
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- Citation
A retrospective survey to study the prevalence of maternal modifiable risk factors leading to cleft lip and/or palate in cases reporting to a tertiary care centre in Navi Mumbai
- Author Details:
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Pradnya Atish Korwar *
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Adil Gandevivala
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Srivalli Natarajan
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Ravindranath VK
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Anjali Gourishankar Gheware
Introduction: Orofacial clefts (OFC) encompass a variety of disorders impacting the lips and oral cavity. As a multifactorial condition, OFC is influenced by both genetic and environmental risk factors. Children affected by OFC require multidisciplinary care from birth through adulthood.
Aim: This study aims to evaluate ways of preventing the development of OFC’s through understanding the maternal modifiable risk factors leading to such congenital defects in offsprings.
Materials and Methods: This cross-sectional questionnaire-based study, was carried out in MGM Dental College & Hospital, Navi Mumbai. A questionnaire was fabricated that included 11 parameters. 127 cases of cleft lip & or palate were interviewed. Data was analysed to evaluate the prevalence of different factors leading to development of cleft lip and palate.
Results: There was a general tendency for females to be more affected, with cleft palate being more commonly observed in females. Unilateral and left sided clefts were more common. 63% cases were socioeconomically below poverty line, consanguineous marriages accounted to 12.6%. 15% of the mothers reported passive smoking through a family member during pregnancy and 44% mothers reported usage of chulha for cooking. 70.8% mothers reported use of multi-vitamins and folic acid supplementation during pregnancy and 52% mothers gave a history of polished rice consumption during pregnancy.
Conclusion: Maternal active smoking, passive smoking, consanguineous marriage, polished rice consumption should be discouraged. Use of clean-burning cookstoves, multi-vitamins and folic acid supplementation, genetic counselling should be encouraged. Patient-centric solutions should be implemented for the prevention and management of such cases.
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How to Cite This Article
Vancouver
Korwar PA, Gandevivala A, Natarajan S, VK R, Gheware AG. A retrospective survey to study the prevalence of maternal modifiable risk factors leading to cleft lip and/or palate in cases reporting to a tertiary care centre in Navi Mumbai [Internet]. J Contemp Orthod. 2025 [cited 2025 Oct 28];9(4):515-522. Available from: https://doi.org/doi: 10.18231/j.jco.8168.1758887466
APA
Korwar, P. A., Gandevivala, A., Natarajan, S., VK, R., Gheware, A. G. (2025). A retrospective survey to study the prevalence of maternal modifiable risk factors leading to cleft lip and/or palate in cases reporting to a tertiary care centre in Navi Mumbai. J Contemp Orthod, 9(4), 515-522. https://doi.org/doi: 10.18231/j.jco.8168.1758887466
MLA
Korwar, Pradnya Atish, Gandevivala, Adil, Natarajan, Srivalli, VK, Ravindranath, Gheware, Anjali Gourishankar. "A retrospective survey to study the prevalence of maternal modifiable risk factors leading to cleft lip and/or palate in cases reporting to a tertiary care centre in Navi Mumbai." J Contemp Orthod, vol. 9, no. 4, 2025, pp. 515-522. https://doi.org/doi: 10.18231/j.jco.8168.1758887466
Chicago
Korwar, P. A., Gandevivala, A., Natarajan, S., VK, R., Gheware, A. G.. "A retrospective survey to study the prevalence of maternal modifiable risk factors leading to cleft lip and/or palate in cases reporting to a tertiary care centre in Navi Mumbai." J Contemp Orthod 9, no. 4 (2025): 515-522. https://doi.org/doi: 10.18231/j.jco.8168.1758887466